CholesteHelp, a supplement sold by Kobayashi Pharmaceutical, contains a highly toxic compound called puberulic acid, which is a product of mold. This compound has been potentially linked to 80 deaths and numerous hospitalizations, leading to a recall of the product in Japan and China.
CholesteHelp is a supplement that claimed to help reduce cholesterol levels1. It contained a highly toxic compound called puberulic acid, which is a product of mold1. The supplement was sold in Japan and China and has been linked to multiple deaths and hospitalizations, leading to a recall of the product.
Puberulic acid in CholesteHelp is believed to have originated from blue mold contamination during the production process of the supplement's red yeast rice ingredient. The mold generated the acid, which is a toxic natural compound, and it was subsequently discovered in the supplements. This contamination is suspected to have occurred at Kobayashi Pharmaceutical's aging factory in Osaka, which was shut down in December due to obsolescence.